Cellular Immunity in Aging
نویسندگان
چکیده
منابع مشابه
Cellular Immunity in Vitro
An in vitro model of cellular immunity in the guinea pig was established. Animals were immunized with tubercle bacilli, bovine gamma globulin, or picrylated human serum albumin in complete Freund's adjuvant. Oil-induced peritoneal exudates from immune and control animals were cultured overnight with and without specific antigen. The cultures were washed and the macrophage monolayers were infect...
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Considerable advances have been made recently in our understanding of the pathogenesis and the immunological mechanisms involved in the prevention and control of infection by Bordetella pertussis. Traditionally , research on protection has focused on the role of humoral immunity and several reports have shown that passive transfer of antibodies against several putative protective antigens, incl...
متن کاملCellular Immunity in Vitro
When sensitive lymphocytes are cultured with the appropriate antigen, lymphoblasts appear after 24-48 hr of incubation and the number of these increases steadily from the 2nd to the 6th or 7th day. Our problem was to discover, at a cellular level, how this increase takes place; whether it is a massive response of many cells, stepwise recruitment of cells into the lymphoblast class, or simply re...
متن کاملTetraspanins in cellular immunity.
Tetraspanins are a superfamily of integral membrane proteins involved in the organization of microdomains that consist of both cell membrane proteins and cytoplasmic signalling molecules. These microdomains are important in regulating molecular recognition at the cell surface and subsequent signal transduction processes central to the generation of an efficient immune response. Tetraspanins, bo...
متن کاملAging, immunity, and cancer.
BACKGROUND The prime function of the immune system is to protect the entire organism from a variety of insults and illnesses, including the development of cancer. The question of how age-related declines in immune function contribute to an increasing incidence of malignancies continues to be a focus of discussion and speculation. METHODS The recent literature from the National Library of Medi...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1979
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12532755